Endocrine Abstracts

Background: The active form of vitamin D, 1,25(OH)2D, plays a key role in regulating calcium and phosphorus metabolism and bone homeostasis. In paediatrics, maintaining optimal 1,25(OH)2D levels is crucial for supporting musculoskeletal growth. The hormone also serves as a diagnostic indicator for multiple disorders such as vitamin-D dependent rickets. Current Literature lacks comprehensive reporting of age-specific reference ranges in pa...

Background: Fibroblast growth factor 23 (FGF23) is a key protein in bone homeostasis regulatingserumphosphateand calcitriol (1,25(OH)2D3) concentrations. Analytical performance and reference ranges of FGF23 assays differ by molecule assayed (intact or C-terminal FGF23) and manufacturer. We aim to establish reference interval values for both cFGF23 and iFGF23 in a paediatric population.Methods: Writt...